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SERUM TESTOSTERONE “LOWER”IN MEN WITH BPH, HAIR LOSS

     As we previously reported, an age related decline in the testosterone to estrogen ratio in favor of estrogen has been shown to disrupt immune synchronization and increase the overall incidence of hair loss, prostate enlargement, and abdominal fat accumulation creating what is clinically termed the “estrogen syndrome”. It is well known that men with enlarged prostates are much more likely to have androgenetic alopecia, or MPB.

     While finasteride (Propecia/Proscar) decreases serum DHT, it also is thought to increase estrogen which suggests that men over 35 may want to consider using it in conjunction with a systemic aromatase inhibitor such as Chrysin/Piperine (Super Miraforte), Arimidex, or stinging nettle extract, to maximize its hair growth effects and minimize potential side effects (that are listed in the PDR) such as Gynocaemastia (breast enlargement in males), sexual side effects, and an increase in fat deposition. These compounds have been reliably shown to increase testosterone and reduce excess estrogen, resulting in a youthful hormone profile that optimizes immune function and to some degree, body composition

     Those contemplating testosterone replacement therapy who are also concerned about hair loss would be advised to use testosterone only in conjunction with a 5-alpha-reductase inhibitor and, possibly and aromatase inhibitor as well.


Following are excerpts of abstracts after a basic review of the medical literature:

1. J. Urol. 99 (1968) p. 788-92 2. Gerontol. 14 (1968) p. 133-41 3. J. Lab. Clin. Med. 76 (1970) p. 530-6 4. J. Ster. Bio. 6 (1975), p. 1373-9 5. J. Endoc. 69 (1976) p. 15P 6. Prog. Clin. Biol. Res. 6 (1975) p. 143-58 7. J. Endoc. 71 (1976) p. 99-107 8. Probl. Endokrinol. 23 (1977) p. 111-4 9. Cancer Res. 38 (1978) p. 4126-34 10. Experientia 35 (1979) p. 844-5 11. J. Endoc. 83 (1979) p. 31P 12. Vestn. Akad. Med. Nauk USSR 3 (1980) p. 72-7 13. Klin. Exper. Urol. 4 (1982) p. 1930 14. J. Ster. Bio. 22 (1985) p. 521-8 15. Rocz. Akad. Med. Supl. 42 (1984) p. 177 16. Rev. Esp. Fisiol. 46 (1990) p. 63-8 17. Rev. Esp. Fisiol. 47 (1991) p. 161-6 18. Zhonghua Yixue Zazhi 73 (1993) p. 489-90 19. Prostate 27 (1995) p. 25-31 20. Brit. J. Urol. 77 (1996) p. 433-40 21. Cancer Epidem. Bio. Prev. 4 (1995) p. 735-41 22. Proc. Nat. Acad. Sci. 93 (1996) p. 11802-7 23. J. Clin. Endoc. Metab. 82 (1997) p. 571-5 24. Hormone Behav. 31 (1997) p. 110-19 25. Cancer Epidem. Bio. Prev. 6 1997) p. 967-9 26. Endoc. Japan 19 (1972) p. 97-106 27. Steroids 52 (1988) p. 237-47 28. Proc. Nat. Acad. Sci. 95 (1998) p. 11083-8

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