Pregnenolone is made directly from cholesterol within the mitochondria of the adrenal glands and, to a lesser degree, the nervous system, with the help of the cholesterol side chain cleavage enzyme, p450scc. Pregnenolone is a precursor to various hormones, such as progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens. Healthy, high levels are essential for mood modulation, stress management, and cognition. It also helps the body maintain normal hormone levels, which in turn regulates numerous body functions. Finasteride (Propecia, Proscar) is well documented to significantly diminish Pregnenolone, predisposing many finasteride users to Depression, Anxiety, and measurable Cognitive decrements. Finasteride users may consider supplementing with Pregnenolone to offset these neurological effects.
Directions: Take one capsule daily preferably early in the day on an empty stomach, or as recommended by a healthcare practitioner.
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