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Study: Ginseng Stimulates Hair Growth (Better than Propecia)
Ginseng is touted in Traditional Chinese Medicine (TCM) as a frontline treatment for Hair Loss in various forms, particularly Androgenetic Alopecia, or Male Pattern Baldness. TCM has an excellent and well supported track record in treating a huge variety of disorders. Treatment typically entails the use of highly individualized, multi-component herbal preparations, and occasionally Acupuncture. We have collaborated with patients and TCM practitioners on individual hair loss treatment protocols in several cases, and though all formulations used were different, they had the common denominator of Ginseng.
The following study sheds some light on the specific mechanisms by which Ginseng functions as a viable intervention for MPB, Of interest as well is that its effects on stopping hair loss and inducing hair growth were confirmed to be significantly better than finasteride,(Propecia).
Ginsenosides are naturally occurring components of Ginseng. Highly absorbable Ginseng Extracts are used in studies that yield high levels of specific Ginsenosides.
Biol Pharm Bull. 2014;37(5):755-63.
Ginsenoside F2 reduces hair loss by controlling apoptosis through the sterol regulatory element-binding protein cleavage activating protein and transforming growth factor-β pathways in a dihydrotestosterone-induced mouse model.
Shin HS1, Park SY, Hwang ES, Lee DG, Mavlonov GT, Yi TH.
This study was conducted to test whether ginsenoside F2 can reduce hair loss by influencing sterol regulatory element-binding protein (SREBP) cleavage-activating protein (SCAP) and the transforming growth factor beta pathway of apoptosis in dihydrotestosterone (DHT)-treated hair cells and in a DHT-induced hair loss model in mice. Results for ginsenoside F2 were compared with finasteride. DHT inhibits proliferation of hair cells and induces androgenetic alopecia and was shown to activate an apoptosis signal pathway both in vitro and in vivo. The cell-based 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay showed that the proliferation rates of DHT-treated human hair dermal papilla cells (HHDPCs) and HaCaTs increased by 48% in the ginsenoside F2-treated group and by 12% in the finasteride-treated group. Western blot analysis showed that ginsenoside F2 decreased expression of TGF related factors involved in hair loss. The present study suggested a hair loss related pathway by changing SCAP related apoptosis pathway, which has been known to control cholesterol metabolism. SCAP, sterol regulatory element-binding protein (SREBP) and caspase-12 expression in the ginsenoside F2-treated group were decreased compared to the DHT and finasteride-treated group. C57BL/6 mice were also prepared by injection with DHT and then treated with ginsenoside F2 or finasteride. Hair growth rate, density, thickness measurements and tissue histotological analysis in these groups suggested that ginsenoside F2 suppressed hair cell apoptosis and premature entry to catagen more effectively than finasteride. Our results indicated that ginsenoside F2 decreased the expression of TGF and SCAP proteins, which have been suggested to be involved in apoptosis and entry into catagen. This study provides evidence those factors in the SCAP pathway could be targets for hair loss prevention drugs.
Here is a sampling of many other studies that have been published showing the beneficial effects of Ginseng on hair growth:
*The ginsenosides of Panax ginseng promote hair growth via similar mechanism of minoxidil. -2015
* Red ginseng extract promotes the hair growth in cultured human hair follicles.-2014
* The inductive effect of ginsenoside F2 on hair growth by altering the WNT signal pathway in telogen mouse skin.-2014
* Effects of ginseng rhizome and ginsenoside Ro on testosterone 5a-reductase and hair re-growth in testosterone-treated mice.-2011
Ginseng’s unique active ingredient ginsenosides, possess important medicinal properties. Key ginsenosides from ginseng extract are not fully absorbed until they reach the lower intestine.
With standard commercially available ginseng extracts there is a huge individual variation in capability of metabolizing ginsenosides. Absorption is inconsistent, and there is a variable range of times needed to attain maximum plasma concentration. Often, only a small amount of ginseng is absorbed. Many people do not fully absorb ginseng.
The most potent Ginseng Extract on the market today, used in 16 recent published studies is GS15-4 Extract, a specifically fermented form of the Panax ginseng root, that produces a 4 times faster absorbtion and 15 times more overall absorption compared to the widely available non-fermented Standardized Extracts.
When GS15-4 extract is taken, absorption is enhanced by a factor of 15. It is the beneficial bacteria in GS15-4 that play a pivotal role in metabolizing natural ginsenosides into highly absorbable compounds.
GS15-4 is considered to be the 21st Century Ginseng.
Asian Energy Boost combines GS15-4 Ginseng Extract along the potent Asian mushroom Cordyceps Sinensis. Combined, they deliver potent energy support.
Cordyceps has a long history of use in TCM. It is a rare combination of a caterpillar and a fungus and found at altitudes above 4500 m in the Himalayas. It is primarily used for strengthening the immune system, improving athletic performance, reducing the effects of aging, and promoting longer life. It often shows up in the hair loss formulations of TCM.
Its benefits for hair growth could likely be attributed to its ability to protect mitochrondrial DNA, and most significantly inhibit Matrix Metalloproteinase-9 (MMP-9) a collagen enzyme that induces apoptosis in the hair bulb.
How is Asian Energy Boost used?
Asian Energy Boost has a broad beneficial effect on health and well- being. It is virtually non- contra indicative.
It harmonizes and augments a broad range of hair loss treatment protocols and supplements. So the applications for GS15-4 are remarkably diverse as a stand -alone supplement for athletic performance, body building, overall health, stress management, or as part of an existing hair loss treatment regime.
Serving Size 1 vegetarian capsule Asian Energy Boost contains:
To consult with our Hairloss Expert in person about the most advanced hair loss treatment protocols, call toll free: 1-888-577-HAIR(4247), (321)733-5933 9-9PM EST Or E-mail us at MPBResearch@aol.com
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