IMMUNOSTIMULATION, AND MPB
It has been established that cortisol, the “stress” hormone and
estrogen are significantly elevated in individuals with androgenetic
alopecia, which is immunosuppressive.
It is also known that balding is essentially an interplay between
hormones (notably DHT, Androstendione, Estrogen) and immunologically mediated
inflammation, essentially causing the body to treat hair follicles like
organs being rejected. Dr.
Proctor and Dr. Rushton of Bioscientic Ltd., among others, contend that this
immunological rejection and the inflammation associated with it is much more
significant and primary to balding than the androgens, which simply play a
role in initiating the process. That
is why antiandrogens are fairly effective at preventing further loss, but
initiate little to no regrowth, except for very recently lost hair.
Several prominent researchers have been issued multiple patents for
immunostimulation based, hair loss treatments aimed at neutralizing existing
follicular inflammation. Their
research and recommendations will be integrated into our treatment protocol
to provide an even more comprehensive treatment approach, in addition to
enhancing the overall health of the individual.
The recommended compounds for hair growth via immunostimulation are:
Growth Hormone (GH) Releasers – Growth Hormone has been reliably
shown to increase muscle mass, thicken skin, reduce body fat index and grow
scalp hair. Injections are quite
expensive, but coming down in price.
Arginine/Lysine at 4 grams each stimulate thymic functioning, and GH
release, Dr. Rushton, of Bio Scientific Ltd. Has a patent on L-Lysine as a
hair growth treatment.
Anti-aromatases (in males) or estrogen antiagonists.
Soy extract, acts as a “phytoestrogen” which competes with
estrogen at the receptor site, neutralizing estrogenic stimulation of
androgen mediated processes. Daidzen,
a soy isoflavone, also appears to regenerate thymus in males.
Dr. Sheffield has been issued patents on anti-aromatases as hair-loss
agents. One mention here: anti-aromatases
in females cause hairloss, whereas in men they appear to have the opposite
effect. They also have a
negative effect on thymic functioning in females, and a positive effect in
Androgen antagonists/DHT inhibitors.
Vit A/Beta Carotene
Gaba – sublingually (may also interrupt stress axis which is
detrimental to thymic functioning. Gaba
transminase levels decrease with age.
At the root of this phenomena of age related immune system decline is a process known as “thymic involution” (deterioration of the thymus gland functioning), which is genetically predetermined, and responsible for an age related cascade of events and inflammatory autoimmune process including arthritis and balding.