Nizoral Shampoo mildly inhibits the binding of DHT to the hair follicle androgen receptor. Additionally it likely suppresses the localized autoimmune responses through its effects on specific cytokines that are related to dandruff and perifollicular inflammation (present in 98% of balding men).
There have been 2 studies published in the medical literature confirming that 2% Nizoral shampoo grows hair in balding men with continued usage. It appears to cure scalp inflammation and reduces sebum levels confirming its antiandrogenic effect. Numerous anecdotal reports and a recent study would seem to indicate that the 1% over the counter version is also helpful for hair loss.
Directions: Shampoo daily or, 2 days on, 1 day off.
Side effects: Dry scalp and hair.