Out of prostate research comes some interesting findings about Vitamin E Succinate that could have possible implications for male pattern loss, which is largely mediated by the same hormonal factors implicated in prostate enlargement and prostate cancer. It was only the succinate version of vitamin E that produced these specific effects, which is inexpensive and widely available. A study published in the May 28 2002 issue of the Proceedings of the National Academy of Sciences(https://www.pnas.org/ ) has revealed previously unknown mechanisms of action for vitamin E succinate against prostate cancer. Vitamin E had been associated with a lower incidence of prostate cancer in epidemiologic studies and the succinate form of the vitamin has been shown to inhibit cancer growth in several studies.
The University of Rochester researchers used an androgen-dependent human prostate cancer cell line to find out how vitamin E succinate prevents and combats cancer. In one experiment, vitamin E succinate was compared to the antiandrogen drug flutamide. While the addition of flutamide largely failed to combat growth stimulated by the addition of the androgen dihydrotestosterone (DHT), vitamin E succinate proved to be successful. However, when both compounds were added, a further repressing of DHT-mediated cell growth was observed. When tumor cells were replaced with cell cultures from normal prostate tissue, the same amount of vitamin E succinate only slightly inhibited cell growth, suggesting that the vitamin may selectively inhibit tumor cells that are androgen sensitive.
In another experiment that sought to determine the effect of vitamin E succinate on prostate specific antigen (PSA), a marker for prostate cancer, PSA expression was induced by the addition of DHT to the cell culture. When vitamin E was added, intracellular and secreted levels of PSA expression were repressed. This occurred together with down-regulation of androgen receptor protein levels. The androgen receptor is required for the initiation and progression of prostate cancer and Male Pattern Hair Loss. The authors write that vitamin E succinate may suppress the growth of prostate cancer and the expression of PSA “by inhibiting androgen receptor expression at both the transcription and translation levels.” An oral dose of 800 i.u.’s would be appropriate to produce these effects.
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- Updates September 15, 2018
- Resveratrol Inhibits DHT-inducible IL-6, JAK in Hair Miniaturization September 14, 2018
- Hello world! August 21, 2015
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- 5-LOX , A Therapeutic Target in Hair Loss Treatment
- 98 % 5 Alpha Reductase Inhibition with Astaxanthin!
- A Confirmed Role for Both Metformin and Ashwagandha in Hairloss Treatment
- A Gene Theraphy in the Making
- A Hairloss Treatment Pill for Men and Women from L’Oreal
- A New Topical Anti-Androgen from Europe
- A Role for Anti-Oxidants in Treating MPB
- About Us
- Abstract IGF-1
- Advanced Extracts of Saw Palmetto and Dietary Lignans- A Comprehensive and Safe Hormonal Treatment of MPB
- Advanced Topical Hair Growth Stimulation
- All the more reason to take Green Tea for hair loss
- Amino Acids
- Anabolic Steroids and Hair Loss Prevention
- Ancient Cures for Hair loss
- Androgenetic Alopecia a Cardiovascular Risk Factor, Isn’t Hair Loss itself bad enough?
- Androgenic Alopecia Associated with less Dietary Soy
- Anti Aging Coaching
- Antibiotics as Potential Treatment Agents
- Apple Polyphenol
- Archives
- Astaxanthin demonstrates a 98% reduction in 5 alpha reductase
- Astaxanthin Prevents Skin Deterioration
- Astaxanthin Supplement lowers DHT
- Best Amino Acids for Hair Growth
- Best Curent Practice, Men & Women
- Beyond a “Balanced Diet”-Foods That Really help with Hair Loss
- Beyond Saw Palmetto: Natural Propecia Alternatives
- Bioavailable Collagen/Keratin Supplement Reverses Age Related Hairloss, Skin Laxity
- Biotin
- Black Tea DHT Reduction(72%) Mechanism Conclusively Identified
- Black Tea like Propecia and Minoxidil Combined
- Black Tea/Green Tea/ Soy/Seaweed- A Potent Asian Hairloss Prevention/Treatment Dietary Combination
- Both Finasteride and Resveratrol stop apoptosis; programmed cell death, in Androgenetic Alopecia
- Both finasteride, and Tea catechins reduce serum DHT. Why no side effects for Tea catechins ??
- BOTOX: A Possible Cure for Alopecia Areata
- Branched Amino Acids
- Branched Chain Amino Acids Promote Hair Growth
- Caffeine
- Carnitine and Hairloss
- Carnitine Tartrate
- Cayenne, Soy Combo for Hairloss
- Chronic Inflammation, Hair Loss, and What You Can Do About It
- Circulation is Implicated in Hairloss
- Coconut Oil- A Possible Breakthrough Treatment for Alopecia Areata
- Collagen and Keratin Reverse Hair Miniaturization
- Contact Us
- Copper Peptides
- Coronavirus: Tips to Enhance your Immune Function
- Cortisol, Immunostimulation, and MPB
- Could This Simple Supplement Combo Treat Hair loss better than Propecia?
- Creatine Raises DHT, But Don’t Panic
- Curcumin Degrades Androgen Receptors
- Curcumin Elite
- Curcumin Use Reinforced For Hairloss Treatment
- Curcumin Use Reinforced For Hairloss Treatment
- Curcumin Yet More Evidence
- Curcumin, A 5-Alpha Reductase Type 2 Inhibitor
- Cutaneous levels of IGF-1, a Therapeutic Target for MPB
- Dairy Consumption and Hairloss
- DHEA and Hairloss
- Diabetes, Hair loss, Green Tea
- Diet, Inflammation, and Hair Loss
- Discovery: N-Acetyl-Cysteine Effectively Inhibits Prostaglandin D2
- Dr. Holick, MD, PhD: Emu Oil Study on Skin Enhancement and Hair Growth
- Dr. Mercola on Insulin Resistance, Diet and Hair loss
- Dutasteride Approved
- Editor’s Desk
- Effects of Propecia documented to be Permanent
- Emotional Consequences of Finasteride: Fool’s Gold
- Emu Oil
- Emu Oil & Wrinkles: Firming the Facial Collagen Matrix
- Emu Oil and Hair Regrowth: Critical Factors in Efficacy
- Emu Oil Description
- Emu Oil Hairloss and Frontal Regrowth
- Emu Oil Increases Rogaine Hair Growth
- Emu Oil Outperforms Minoxidil, Minoxidil/Retin A, and Nizoral
- Emu Oil Patent; 80% Hair Growth Stimulation
- Emu Oil Regenerates Skin and Hair Follicles Even in Burns
- Emu Oil Supplement Facts
- Emu Oil That Can Actually Grow Hair
- Emu Oil Update
- Emu Oil, Dr. Sears, and Hairgrowth Mechanisms
- Emu Oil, Hair Growth, and Facial Rejuvenation
- Emu Oil, PGE2, Hair Growth Stimulation
- Enhance Rogaine,Other Topical Treaments with Emu Oil
- Estrogen Alternatives in Women’s Hairloss
- Estrogen’s Role in Hair Loss Elucidated
- Even Extra-Strength Rogaine Offers Little Hope
- Even Extra-Strength Rogaine Offers Little Hope
- EXCESS SYSTEMIC ESTROGEN IN MEN AND HAIRLOSS
- Extreme Hairloss Intervention
- Facilitating Equol Production for Hair Loss Treatment
- Fibrosis Leads to Destruction of Hair Follicles in Advanced cases of MPB
- Finally- A Hair Cloning/Multiplication Breakthrough from China
- Finally- a Topical Stem Cell Treatment for Hair Loss
- Flaxmeal, Coconut Oil and Hairloss
- For Men: Ancient Chinese Secrets for Hairloss
- Further Evidence of the Testosterone Boosting Effects of Black Tea
- German Research Confirms Stress a Major Factor in MPB
- GHO Hair Multiplication
- GINKGO BILOBA, MICROCAPILLARY CIRCULATION, HAIR GROWTH
- Grape Seed Extract
- Grape Seed Extract Benefits Hair loss via Multiple Mechanisms
- Green Tea : New Evidence as a Treatment for Hairloss
- Green Tea and Hairloss
- Green Tea Promotes Hair Growth Via Sonic Hedgehog Gene Activation
- GREEN TEA RAISES SHBG-HAIRLOSS/MPB BENEFIT SHBG Levels and Hair Loss
- Green Tea, Grape Seed identified as Novel Treatments for Hair Loss
- Green Tea/Soy Combination Additional Mechanisms that Benefit Hairloss
- Growth Hormone IGF-1 and Hair Growth
- Hair Growth Effects of Pumpkin Seed Oil
- Hair Growth with Nizoral Cream
- Hair Loss Treatment in Tough Economic Times
- Hair Loss Treatments You’d be Crazy Not to Use
- Hair Regeneration Using Adipose-Derived Stem Cell Proliferation with Emu Oil
- Hair-Growth Potential of Ginseng and its Major Metabolites: A Review on its Molecular Mechanisms
- Hair-Growth Potential of Ginseng and its Major Metabolites: A Review on its Molecular Mechanisms
- Hairloss Prevention During Chemotherapy
- Hairloss Remedies from Traditional Chinese Medicinal Systems
- Hairloss Research Home
- Head and Shoulders for Hair Loss?
- Herbal Aromatase Inhibition
- Higher testosterone Equals Lower DHT levels in Aging Men
- Home
- How Emu Oil Stimulates Frontal Hair Growth
- How to Address the Inflammatory Components of Hairloss
- How to Quickly Reduce Shedding
- How Tocotrienols Promote Hair Growth
- Huge quality (and hair growth potential) difference in commercially available Emu Oils
- Human Hair Growth Enhancement by Green Tea
- IGF-1 a Therapeutic target for Androgenetic Alopecia
- Indena Patents a Hairloss Treatment
- Index
- Inhibition of Inflammation in Hair loss
- Insulin Resistance and Hairloss
- International Literature Review Concludes Green Tea Effective with Hair Loss
- Italian Patent Details Hair Growth Effects of Resveratrol/Curcumin Combination
- Italian Research Team: Apple Polyphenol Supplements Reverse both Androgenetic and Chemo Therapy Induced Hairloss
- Italian Study: Propecia Psychiatric Side Effects Persist After Discontinuation
- Just Published: Antioxiants Promising Treatments For Pattern Hairloss
- Keratin for Hair Growth: How it works
- Keratin for Hair Growth: How it works
- Ketoconazole
- L’Oreal Real Patents an Oral Taurine Nutrient Compound For The Treatment of Androgenic Alopecia
- L-Lysine
- L-Lysine and the Treatment of Hairloss
- Lauric Acid, Myristic Acid (Coconut Oil) Reduces DHT Comparable to Finasteride
- Like Proscar and Avodart, Lycopene stops BPH in its tracks
- Literature Review: Soy NOT Feminizing, Beneficial for Hair
- Low Sex Hormone Binding Globulin a Marker for MPB
- Low Temperature Processed Emu Oil
- Lysine – A Cheap, Effective Co-Treatment for Hairloss
- Malassezia
- Mega Green Tea Extract
- Melatonin Downregulates Androgen Receptor Activity
- Metabolic Syndrome Tied to Hairloss
- Minoxidil Alternatives
- More Evidence For Soy As A Hair Growth Agent
- More Evidence for Taurine
- More Evidence than IGF-1 stimulates Hair Growth
- More Good News on Cayenne Pepper Consumption and Hair Growth
- More on Soy and Hairloss
- More than 95% with MPB are deficient in Branched Chain Amino Acids, Cysteine
- N-Acetyl-L-Cysteine
- Natural Estrogen with Pomegranate Extract(women)
- Natural Hair Loss Treatment-a Practical, Scientific Approach
- Natural Hair Loss Treatments: MPB Research Summary and Core Recommendations
- Nestle and L’Oreal Launch a New Taurine Based Pill for Hairloss
- New Dandruff Shampoo for Hairloss
- New Emu Oil Regrowth Pictures
- New Emu Oil Study from England
- NEW HAIR GROWTH SHAMPOO LOOKS LEGIT
- New Italian Hair Growth Nutraceutical Combines Soy, Apple Polyphenol, Beta Sitosterol and Melatonin
- New Italian hair growth nutraceutical combines Soy, Apple Polyphenol, Beta Sitosterol and Melatonin
- New Research Sheds Light on Resveratrol, Green Tea Hair Growth Mechanisms
- New Study Shows Saw Palmetto Super Critical Extract To Be As Bioactive As The Leading Prescription Drug for Hair Loss
- New Study Validates Hair Growth Mechanism of Resveratrol/Curcumin
- NEW STUDY: Black Tea Extract Promotes Hair Growth
- New Study: Curcumin Inhibits 5 Alpha Reductase
- New Study: Emu Oil Facilitates Hair Follicle Restoration
- New Study: Ginkgo Promotes Hair Growth
- New Study: Low Dose Astaxanthin Supplementation Rejuvenates Facial Skin
- New Study: Oral Apple Polyphenol Extract Promotes Hair Growth
- New Study: Unlike Propecia, Saw Palmetto actually enhances Male Functioning
- New Super Absorbable Tocotrienols
- New Updates
- Nizoral 1% Study SHOWS Benefits for Pattern Balding
- Nizoral Combo Study
- Nucleic Acid Therapy for Aging and the Diseases of Aging
- Nutritional Intervention Reverses Damage to Hair and Skin
- Optimize Your Hormone Profile for Health and Hair Growth
- Optimized Carnitine
- Optimized Resveratrol
- PalmettoGuard Saw Palmetto
- Pantothenic Acid: Treatment Implications
- PATENT: Fish Oil for Hair Growth
- Patent: Pharmaceutical Composition Comprising Curcumin and Resveratrol for Hair Growth
- Peppermint Tea for Hairloss
- Post Rogaine Shed Documented in Archives of Dermatology
- Preventing Hair loss While on Anabolic Steroids
- Preventing/Management of Propecia Side Effects
- Progesterone
- Progesterone Cream- Hairloss Treatment for Men
- Proof That Hair Follicles Never “Die”
- Propecia Alternatives
- Propecia and Breast Cancer
- Propecia Less effective in those over 26 years old
- Propecia Linked with Infertility, Avodart causes Erectile Dysfunction in 100% of Rats
- Propecia Reduces DHT by 71% Black Tea Reduces DHT by 72%
- Propecia Side Effects
- Propecia, Depression and Dementia
- Propecia/Avodart Effective in Women
- Propecia/Avodart Grows More Than Hair!
- PROPECIA: Disturbing Implications for Stress Management, OCD, and Substance Abuse
- Propecia: The Pros, Cons, and Alternatives
- Published Study: Emu Oil Enhances Effectiveness of Minoxidil
- Published Study: Massage Does Stimulate Hair Growth
- Quercetin – A Possible Breakthrough Treatment for Alopecia Areata
- Recently Published Study Validates Hair Growth Effects of Saw Palmetto
- Reduced Biotin and Zinc Levels Found in MPB
- Replacing Propecia
- Response to MPB Treatment related to plasma Zinc levels
- Response to MPB Treatment related to plasma Zinc levels
- Response to Propecia or Avodart May Depend on Your Genes
- Resveratrol and Menopausal Hair Loss-Treatment Implications
- Resveratrol Inhibits DHT IL-6 JAK in Hair Miniturization
- Resveratrol Provides New Breakthrough in Male Baldness
- Resveratrol, a Possible Hair Growth Mechanism
- Reversing Reduced Stem Cell Activation Associated with Age Related Hair Loss
- Rooibos
- Saw Palmetto and Hairloss Treatment
- Saw Palmetto Reduces 5AR, Raises Testosterone
- Saw Palmetto, Propecia and Hairloss Revisited
- Scalp Thickness, Retin A, Emu Oil and Hair Growth
- Scalp Thickness, Retin A, Emu Oil and Hair Growth
- Scalp Thickness, Retin A, Emu Oil and Hair Growth
- Seasonal Stress and Hairloss
- Seaweed Added to Soy May Facilitate Equol Production
- Serum Testosterone “Lower” in Men with BPH, Hairloss
- Significantly Enhanced Absorption of Green Tea
- Simultaneous Inhibition of DHT, Estrogen and Androstenedione
- Skin Traps
- Soy Extracts Upregulate VEGF
- Soy Isoflavone Suplements Lower DHT And Stimulate Equol Production
- Soy Isoflavone Supplements Lower DHT and Stimulate Equol Production
- Soy Isoflavones for Hair Loss and Skin Aging
- Soy Isoflavones Lower Serum DHT
- Soy May Help Men Protect Against Baldness, Prostate Cancer and Heart Disease
- Soy May Help Men Protect Against Baldness, Prostate Cancer and Heart Disease
- Soy Metabolite Could Halt Hairloss and Prostate Cancer
- Soy/Curcumin a Viable Propecia Replacement
- Soybean and hair loss prevention : evidently, there is a link
- Soybean and hair loss prevention : evidently, there is a link
- Spearmint for PCOS Related Hairloss
- Specific Anabolic Steroids and Hairloss: A Guide
- Stem Cell Research Update
- Steroids and Hairloss
- Stimulate Hair Growth and Have Yunger Skin With Astaxanthin
- Strategic use of Soy and Saw Palmetto with Propecia
- Stress Induced Hair Loss-and What You Can do About it
- Stress, Neurogenic Inflammation and Hair Loss
- Study validates Black Tea Extract as a Treatment for Acne, Male Pattern Baldness
- Study: Ashwagandha Reverses Long Standing Androgenetic Hairloss
- Study: Curcumin on a par with Finasteride at Neutralizing BPH,MPB Hormonal Factors
- Study: Effects of Processing, Diet on Antioxidant Properties of Emu Oil
- Study: Emu Oil Inhibits Inflammatory Signals of MPB
- Study: Green Tea Protects from DHT Effects on Genomic Level
- Study: Soy Isoflavones Supplement Causes Marked Reduction in DHT
- Study: Supplement Combo Reverses Androgenic Alpecia
- Study: Supplement Combo Reverses Androgenic Alpecia
- STUDY: Targeting DHT and Inflammation improve Efficacy in Treating Hair loss
- Study: Taurine, Finasteride Effective Against Stress Hairloss
- Substance P
- Sufi Breathing Techinique to Prevent Hairloss and Wrinkles
- Super Absorbable Soy Isoflavones
- Super Absorbable Tocotrienols
- Supplement Combo Represents a Novel Hair Loss Treatment
- Supplements for Hair Growth Validated in New Study
- Supplements to Mitigate Finasteride Side Effects
- Target Pathway just confirmed for treating MPB with select Anti-Oxidants
- Taurine
- Taurine for Hair Loss, Anxiety, and Depression
- Taurine Grows Hair and New Brain Cells
- Taurine, Anti-Aging and Hair Growth Benefits
- TGF-BETA, The Hair Follicle Assassin
- The 5 alpha Reductase Inhibiting Properties of Coconut Oil
- The Anti-DHT Effects of Coal Tar Shampoos
- The Best Drug/Pharmaceutical Hair Loss Treatment
- The Best Shampoos for Hair Loss
- The hair growth and anti-aging properties of Resveratrol/Curcumin
- The Tragedy of Tumeric For Hairloss
- The Use of Soy Isoflavones to Prevent Hairloss and Preserve the Integrity of Existing Hair
- Theaflavin
- Tocotrienols from Red Palm Oil Induce Hair Growth
- Topical Coconut Oil Pre-Wash: The Ultimate Hair Conditioner
- Topical Emu Oil and Coconut Oil for Hair Loss- A Potent Combination
- Topical Retin A and Bethametasone for Hair Growth
- Traditional Chinese Medicine: New Treatment/Prevention for Alopecia Areata, and possibly MPB
- Treating Hair Loss with Anti-oxidants
- Treatment for Woman Suffering from Genetic Hairloss
- Trial Shows MSM Improves Hair and Nail Growth
- Tumor Necrosis Factor Alpha and Hairloss
- UCLA Stumbles on Cure for Hairloss
- Ultra Natural Prostate Formula
- Updates
- Use of Emu Oil for Stimulating Skin and Hair Growth
- Use Proscar, Not Propecia!!
- Vitamin D and Taurine
- Vitamin D3, Iron, B12 Combo Resolves Premenopausal Hair Loss
- Vitamin E Succinate Down Regulates Androgen Activity
- Wheat Consumption Linked to Hair Loss
- Why Does Emu Oil Work so Well?
- World Renowned Researcher Confirms Pivotal role of Inflammation and Fibrosis in MPB
- Xanthine Compound Formula for Hairloss
- Yet another Saw Palmetto Hair Growth
- ZINC CAPS
- Zyrtec a Possible Treatment for Alopecia Areata